YkuQ

• Description: similar to tetrahydrodipicolinate succinylase
  
  

Gene name	ykuQ
Synonyms
Essential	yes PubMed
Product	similar to tetrahydrodipicolinate succinylase
Function	biosynthesis of lysine and peptidoglycan
Gene expression levels in SubtiExpress: ykuQ
Metabolic function and regulation of this protein in SubtiPathways: ykuQ
MW, pI	24 kDa, 4.678
Gene length, protein length	708 bp, 236 aa
Immediate neighbours	ykuP, dapI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, essential genes, biosynthesis/ acquisition of amino acids

The gene

Basic information

• Locus tag: BSU14180

Phenotypes of a mutant

essential PubMed

Database entries

• BsubCyc: BSU14180

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Acetyl-CoA + (S)-2,3,4,5-tetrahydropyridine-2,6-dicarboxylate + H₂O = CoA + L-2-acetamido-6-oxoheptanedioate (according to Swiss-Prot)

• Protein family: transferase hexapeptide repeat family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactors:

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU14180

• Structure: 3R8Y (from Bacillus anthracis, 80% identity, 96% similarity)

• UniProt: O34981

• KEGG entry: [2]

• E.C. number: 2.3.1.89

Expression and regulation

• Operon:

• Expression browser: ykuQ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: