XylR

• Description: transcriptional repressor of the xylA-xylB and xynP-xynB operons
  
  

Gene name	xylR
Synonyms
Essential	no
Product	transcriptional repressor
Function	regulation of xylan and xylose utilization
Gene expression levels in SubtiExpress: xylR
Metabolic function and regulation of this protein in SubtiPathways: xylR
MW, pI	38 kDa, 5.819
Gene length, protein length	1050 bp, 350 aa
Immediate neighbours	xynB, xylA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control

The XylR regulon

• xylA-xylB, xynP-xynB

The gene

Basic information

• Locus tag: BSU17590

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transcription repression of the xylA-xylB and the xynP-xynB operons

• Protein family: ROK (nagC/xylR) family (according to Swiss-Prot)

• Paralogous protein(s): GlcK

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: inducer: xylose

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P94490

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: xylR (according to DBTBS)

• Expression browser: xylR PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: GP270 (erm), GP1302 (aphA3), available in the Stülke lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Wolfgang Hillen, Erlangen University, Germany Homepage