MlpA

• Description: mitochondrial processing peptidase-like, involved in regulation of protease gene expression
  
  

Gene name	mlpA
Synonyms	ymxG
Essential	no
Product	specific processing protease
Function	control of proteolyticc activity
Gene expression levels in SubtiExpress: mlpA
MW, pI	45 kDa, 5.275
Gene length, protein length	1227 bp, 409 aa
Immediate neighbours	ylxY, ymxH
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteolysis

The gene

Basic information

• Locus tag: BSU16710

Phenotypes of a mutant

fivefold increased levels of proteolytic activity in their growth medium PubMed

Database entries

• BsubCyc: BSU16710

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: peptidase M16 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU16710

• Structure:

• UniProt: Q04805

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mlpA PubMed

• Expression browser: mlpA PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant: deletion mutant, available in van Dijl lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Jan Maarten van Dijl, Groningen, Netherlands