MraZ

• Description: Putative DNA-binding protein
  
  

Gene name	mraZ
Synonyms	yllB
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: mraZ
MW, pI	16 kDa, 4.969
Gene length, protein length	429 bp, 143 aa
Immediate neighbours	bshC, mraW
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

The gene

Basic information

• Locus tag: BSU15130

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

Additional information

the E.coli homolog: mraZ

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: mraZ family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • nucleoid (heterogeneous) PubMed

Database entries

• Structure: 1N0G (the homolog from Mycoplasma pneumoniae) PubMed

• UniProt: P55343

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: mraZ-mraW-ftsL-pbpB PubMed

• Expression browser: mraZ PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • 1A817 ( mraZ::erm), PubMed, available at BGSC

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Melanie A Adams, Christian M Udell, Gour Pada Pal, Zongchao Jia
MraZ from Escherichia coli: cloning, purification, crystallization and preliminary X-ray analysis.
Acta Crystallogr Sect F Struct Biol Cryst Commun: 2005, 61(Pt 4);378-80
[PubMed:16511046] [WorldCat.org] [DOI] (I p)

Jean-Christophe Meile, Ling Juan Wu, S Dusko Ehrlich, Jeff Errington, Philippe Noirot
Systematic localisation of proteins fused to the green fluorescent protein in Bacillus subtilis: identification of new proteins at the DNA replication factory.
Proteomics: 2006, 6(7);2135-46
[PubMed:16479537] [WorldCat.org] [DOI] (P p)

Shengfeng Chen, Jaru Jancrick, Hisao Yokota, Rosalind Kim, Sung-Hou Kim
Crystal structure of a protein associated with cell division from Mycoplasma pneumoniae (GI: 13508053): a novel fold with a conserved sequence motif.
Proteins: 2004, 55(4);785-91
[PubMed:15146477] [WorldCat.org] [DOI] (I p)

R A Daniel, A M Williams, J Errington
A complex four-gene operon containing essential cell division gene pbpB in Bacillus subtilis.
J Bacteriol: 1996, 178(8);2343-50
[PubMed:8636036] [WorldCat.org] [DOI] (P p)

A Yanouri, R A Daniel, J Errington, C E Buchanan
Cloning and sequencing of the cell division gene pbpB, which encodes penicillin-binding protein 2B in Bacillus subtilis.
J Bacteriol: 1993, 175(23);7604-16
[PubMed:8244929] [WorldCat.org] [DOI] (P p)