TcyB

• Description: cystine ABC transporter (permease), membrane protein
  
  

Gene name	tcyB
Synonyms	yckJ
Essential	no
Product	cystine ABC transporter (permease), membrane protein
Function	cystine uptake
Gene expression levels in SubtiExpress: tcyB
Interactions involving this protein in SubtInteract: TcyB
MW, pI	26 kDa, 9.932
Gene length, protein length	702 bp, 234 aa
Immediate neighbours	tcyC, tcyA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, biosynthesis/ acquisition of amino acids, membrane proteins

The gene

Basic information

• Locus tag: BSU03600

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • TcyC-TcyB-TcyA PubMed

• Localization: membrane protein PubMed

Database entries

• Structure:

• UniProt: P42200

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: tcyA-tcyB-tcyC (putative) PubMed

• Expression browser: tcyB PubMed

• Sigma factor:

• Regulation: very weakly expressed under all conditions PubMed

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711] [WorldCat.org] [DOI] (I p)

Pierre Burguière, Sandrine Auger, Marie-Françoise Hullo, Antoine Danchin, Isabelle Martin-Verstraete
Three different systems participate in L-cystine uptake in Bacillus subtilis.
J Bacteriol: 2004, 186(15);4875-84
[PubMed:15262924] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)

F Rodriguez, G Grandi
An operon encoding a novel ABC-type transport system in Bacillus subtilis.
Microbiology (Reading): 1995, 141 ( Pt 7);1781-4
[PubMed:7551042] [WorldCat.org] [DOI] (P p)