HelP

• Description: helicase processivity factor
  
  

Gene name	ydcP
Synonyms	ydcP
Essential	no
Product	helicase processivity factor
Function	conjugation and replication of ICEBs1
Gene expression levels in SubtiExpress: helP
MW, pI	13 kDa, 5.309
Gene length, protein length	378 bp, 126 aa
Immediate neighbours	ydcO, ydcQ
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

mobile genetic elements

The gene

Basic information

• Locus tag: BSU04850

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • enables the host-encoded helicase PcrA to unwind the double-stranded ICEBs1 DNA PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96633

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Expression browser: helP PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:
  • A ncRNA is predicted between ydcO and helP PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Jacob Thomas, Catherine A Lee, Alan D Grossman
A conserved helicase processivity factor is needed for conjugation and replication of an integrative and conjugative element.
PLoS Genet: 2013, 9(1);e1003198
[PubMed:23326247] [WorldCat.org] [DOI] (I p)

Irnov Irnov, Cynthia M Sharma, Jörg Vogel, Wade C Winkler
Identification of regulatory RNAs in Bacillus subtilis.
Nucleic Acids Res: 2010, 38(19);6637-51
[PubMed:20525796] [WorldCat.org] [DOI] (I p)