LtaS

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  • Description: polyglycerolphosphate lipoteichoic acid synthase

Gene name ltaS
Synonyms yflE
Essential no
Product major lipoteichoic acid synthase
Function biosynthesis of lipoteichoic acid
Gene expression levels in SubtiExpress: ltaS
Metabolic function and regulation of this protein in SubtiPathways:
Lipid synthesis
MW, pI 74 kDa, 5.202
Gene length, protein length 1947 bp, 649 aa
Immediate neighbours nagP, yflD
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YflE context.gif
This image was kindly provided by SubtiList
[1]   PubMed
LtaS expression.png




























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, membrane proteins, phosphoproteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [2]
  • SubtiList entry: [3]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: LTA synthase family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification: phosphorylated on Thr-297 PubMed
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [4]
  • E.C. number:

Additional information

Expression and regulation

  • Operon: ltaS (according to DBTBS)
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews: PubMed

Nathalie T Reichmann, Angelika Gründling
Location, synthesis and function of glycolipids and polyglycerolphosphate lipoteichoic acid in Gram-positive bacteria of the phylum Firmicutes.
FEMS Microbiol Lett: 2011, 319(2);97-105
[PubMed:21388439] [WorldCat.org] [DOI] (I p)

Original publications