OppB

• Description: oligopeptide ABC transporter (permease)
  
  

Gene name	oppB
Synonyms	spo0KB
Essential	no
Product	oligopeptide ABC transporter (permease)
Function	initiation of sporulation, competence development
Gene expression levels in SubtiExpress: oppB
Interactions involving this protein in SubtInteract: OppB
Metabolic function and regulation of this protein in SubtiPathways: Alternative nitrogen sources
MW, pI	33 kDa, 9.863
Gene length, protein length	933 bp, 311 aa
Immediate neighbours	oppA, oppC
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, utilization of nitrogen sources other than amino acids, genetic competence, phosphorelay, membrane proteins

This gene is a member of the following regulons

ScoC regulon, TnrA regulon

The gene

Basic information

• Locus tag: BSU11440

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • required for the uptake of quorum sensing peptides such as PhrH PubMed

• Protein family: ABC transmembrane type-1 domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • (OppD-OppF)-(OppB-OppC)-OppA PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: P24138

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: oppA-oppB-oppC-oppD-oppF PubMed

• Expression browser: oppB PubMed

• Sigma factor:

• Regulation:
  • expressed in the absence of good nitrogen sources (glutamine or ammonium) (TnrA) PubMed
  • repressed during exponential growth (ScoC) PubMed

• Regulatory mechanism:
  • TnrA: transcription activation PubMed
  • ScoC: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed