YkkE

• Description: formyltetrahydrofolate deformylase
  
  

Gene name	ykkE
Synonyms	purU
Essential	no
Product	formyltetrahydrofolate deformylase
Function	purine nucleotide synthesis
Gene expression levels in SubtiExpress: ykkE
MW, pI	34 kDa, 5.949
Gene length, protein length	900 bp, 300 aa
Immediate neighbours	ykkD, proB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis/ acquisition of nucleotides

The gene

Basic information

• Locus tag: BSU13110

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 10-formyltetrahydrofolate + H₂O = formate + tetrahydrofolate (according to Swiss-Prot)

• Protein family: ACT domain (according to Swiss-Prot)

• Paralogous protein(s): PurN

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O34990

• KEGG entry: [2]

• E.C. number: 3.5.1.10

Expression and regulation

• Operon:

• Expression browser: ykkE PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: