CmpA

• Description: spore coat protein
  
  

Gene name	cmpA
Synonyms
Essential	no
Product	cortex morphogenetic protein A
Function	control of spore cortex assembly
MW, pI
Gene length, protein length	111 bp, 37 aa
Immediate neighbours	ydcI, ydcK
Get the DNA and protein sequences (Ebmeier et al., 2012)
Genetic context

Categories containing this gene/protein

sporulation proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

• Locus tag: not available

Database entries

• DBTBS entry: no entry

• SubtiList entry: no entry

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:
  • orchestrates spore coat and cortex assembly PubMed
  • represses cortex assembly until spore coat assembly successfully initiates PubMed
• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • surface of the developing spore PubMed

Database entries

• Structure:

• UniProt:

• KEGG entry:

• E.C. number:

Expression and regulation

• Operon: cmpA PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE) PubMed

• Regulatory mechanism:
  • SpoIIID: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Matthias Schmalisch, Elisa Maiques, Lachezar Nikolov, Amy H Camp, Bastien Chevreux, Andrea Muffler, Sabrina Rodriguez, John Perkins, Richard Losick
Small genes under sporulation control in the Bacillus subtilis genome.
J Bacteriol: 2010, 192(20);5402-12
[PubMed:20709900] [WorldCat.org] [DOI] (I p)