Btr
- Description: transcription activator (AraC family DNA-binding domain fused to FeuA-like substrate-binding domain), regulation of the feuA-feuB-feuC-ybbA operon
Gene name | btr |
Synonyms | ybbB, yzbC |
Essential | no |
Product | transcription activator (AraC family) |
Function | regulation of iron acquisition |
Metabolic function and regulation of this protein in SubtiPathways: Stress, Metal ion homeostasis | |
MW, pI | 60 kDa, 6.433 |
Gene length, protein length | 1587 bp, 529 aa |
Immediate neighbours | feuA, ybbC |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
acquisition of iron, iron metabolism, transcription factors and their control
This gene is a member of the following regulons
The Btr regulon:
The gene
Basic information
- Locus tag: BSU01640
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s): enterobactin, bacillibactin (co-activators) PubMed
- Effectors of protein activity: enterobactin, bacillibactin (co-activators) PubMed
Database entries
- Structure:
- UniProt: P40408
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: btr PubMed
- Additional information:
- the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References