BceA

• Description: ABC transporter (ATP-binding protein) for the export of bacitracin, plectasin, mersacidin and actagardine
  
  

Gene name	ytsC
Synonyms	bceA
Essential	no
Product	bacitracin ABC transporter (ATP-binding protein)
Function	export of toxic peptides
MW, pI	28 kDa, 9.287
Gene length, protein length	759 bp, 253 aa
Immediate neighbours	bceB, bceS
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

ABC transporters, resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

BceR regulon

The gene

Basic information

• Locus tag: BSU30380

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ABC transporter family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: BceA-BceB PubMed

• Localization: membrane associated (via BceB) PubMed

Database entries

• Structure:

• UniProt: O34697

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: bceA-bceB PubMed

• Sigma factor:

• Regulation:
  • induced in the presence of bacitracin, plectasin, mersacidin and actagardine (BceR) PubMed

• Regulatory mechanism:
  • BceR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Foglino M. PubMed