RlmCD
- Description: rRNA methyltransferase
Gene name | rlmCD |
Synonyms | yerS, yefA |
Essential | no |
Product | rRNA methyltransferase |
Function | 23S rRNA maturation |
MW, pI | 51 kDa, 5.707 |
Gene length, protein length | 1377 bp, 459 aa |
Immediate neighbours | dgkB, yefB |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
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Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06730
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: methylation of U747 and U1939 in 23S rRNA PubMed
- Protein family: COG2265
- Paralogous protein(s): YfjO
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O31503
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Benoit Desmolaize, Céline Fabret, Damien Brégeon, Simon Rose, Henri Grosjean, Stephen Douthwaite
A single methyltransferase YefA (RlmCD) catalyses both m5U747 and m5U1939 modifications in Bacillus subtilis 23S rRNA.
Nucleic Acids Res: 2011, 39(21);9368-75
[PubMed:21824914]
[WorldCat.org]
[DOI]
(I p)