SpoVB

• Description: involved in spore cortex peptidoglycan synthesis
  
  

Gene name	spoVB
Synonyms	spoIIIF
Essential	no
Product	unknown
Function	spore cortex peptidoglycan synthesis
MW, pI	55 kDa, 10.191
Gene length, protein length	1554 bp, 518 aa
Immediate neighbours	comN, yrbG
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, sporulation proteins

This gene is a member of the following regulons

SigE regulon

The gene

Basic information

• Locus tag: BSU27670

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: polysaccharide synthase family (according to Swiss-Prot)

• Paralogous protein(s): YabM, YkvU, YtgP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: Q00758

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: spoVB PubMed

• Sigma factor: SigE PubMed

• Regulation:
  • expressed early during sporulation in the mother cell (SigE, SpoIIID) PubMed

• Regulatory mechanism:
  • • SpoIIID: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Allison Fay, Jonathan Dworkin
Bacillus subtilis homologs of MviN (MurJ), the putative Escherichia coli lipid II flippase, are not essential for growth.
J Bacteriol: 2009, 191(19);6020-8
[PubMed:19666716] [WorldCat.org] [DOI] (I p)

Pradeep Vasudevan, Jessica McElligott, Christa Attkisson, Michael Betteken, David L Popham
Homologues of the Bacillus subtilis SpoVB protein are involved in cell wall metabolism.
J Bacteriol: 2009, 191(19);6012-9
[PubMed:19648239] [WorldCat.org] [DOI] (I p)

Patrick Eichenberger, Masaya Fujita, Shane T Jensen, Erin M Conlon, David Z Rudner, Stephanie T Wang, Caitlin Ferguson, Koki Haga, Tsutomu Sato, Jun S Liu, Richard Losick
The program of gene transcription for a single differentiating cell type during sporulation in Bacillus subtilis.
PLoS Biol: 2004, 2(10);e328
[PubMed:15383836] [WorldCat.org] [DOI] (I p)

D L Popham, P Stragier
Cloning, characterization, and expression of the spoVB gene of Bacillus subtilis.
J Bacteriol: 1991, 173(24);7942-9
[PubMed:1744050] [WorldCat.org] [DOI] (P p)