MurP

• Description: N-acetyl muramic acid-specific phosphotransferase system, EIIBC component of the PTS
  
  

Gene name	murP
Synonyms	ybbF
Essential	no
Product	N-acetyl muramic acid-specific phosphotransferase system, EIIBC component
Function	N-acetyl muramic acid uptake and phosphorylation
MW, pI	47 kDa, 8.496
Gene length, protein length	1365 bp, 455 aa
Immediate neighbours	amiE, murR
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU01680

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

Categories containing this gene/protein

cell wall degradation/ turnover, phosphotransferase systems, utilization of specific carbon sources, phosphoproteins

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: transport and concomitant phosphorylation of N-acetyl muramic acid

• Protein family: PTS permease, sucrose permease (Scr) family PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: Q797S1

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon:

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Ulrike Dahl, Tina Jaeger, Bao Trâm Nguyen, Julia M Sattler, Christoph Mayer
Identification of a phosphotransferase system of Escherichia coli required for growth on N-acetylmuramic acid.
J Bacteriol: 2004, 186(8);2385-92
[PubMed:15060041] [WorldCat.org] [DOI] (P p)

Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040] [WorldCat.org] [DOI] (P p)