Map
- Description: methionine aminopeptidase
Gene name | map |
Synonyms | mapA |
Essential | yes PubMed |
Product | methionine aminopeptidase |
Function | removal of N-terminal methionine from nascent proteins |
Metabolic function and regulation of this protein in SubtiPathways: Nucleotides (regulation) | |
MW, pI | 27 kDa, 6.393 |
Gene length, protein length | 744 bp, 248 aa |
Immediate neighbours | adk, infA |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU01380
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides (according to Swiss-Prot)
- Protein family: peptidase M24A family (according to Swiss-Prot)
- Paralogous protein(s): YflG
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P19994
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulatory mechanism:
- Additional information: strongly expressed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
CongHui You, HongYan Lu, Agnieszka Sekowska, Gang Fang, YiPing Wang, Anne-Marie Gilles, Antoine Danchin
The two authentic methionine aminopeptidase genes are differentially expressed in Bacillus subtilis.
BMC Microbiol: 2005, 5;57
[PubMed:16207374]
[WorldCat.org]
[DOI]
(I e)
J W Suh, S A Boylan, S H Oh, C W Price
Genetic and transcriptional organization of the Bacillus subtilis spc-alpha region.
Gene: 1996, 169(1);17-23
[PubMed:8635744]
[WorldCat.org]
[DOI]
(P p)