TrkA

• Description: cation transport via proton symporter
  
  

Gene name	trkA
Synonyms	yrdP
Essential	no
Product	cation transport via proton symporter
Function	cation uptake
MW, pI	38 kDa, 9.826
Gene length, protein length	1035 bp, 345 aa
Immediate neighbours	yrdQ, czcD
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU26640

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: O07085

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: czcD-trkA PubMed

• Sigma factor:

• Regulation:
  • induced in the presence of toxic metal ions (Zn(II), Cd(II), Co(II), Ni(II) and Cu(II)) (CzrA) PubMed

• Regulatory mechanism:
  • CzrA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Charles M Moore, Ahmed Gaballa, Monica Hui, Rick W Ye, John D Helmann
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Mol Microbiol: 2005, 57(1);27-40
[PubMed:15948947] [WorldCat.org] [DOI] (P p)