Difference between revisions of "HemC"
Line 95: | Line 95: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
+ | ** repressed in the absence of hydrogen peroxide ([[PerR]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/11532148 PubMed] | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
+ | ** [[PerR]]: transcription repression [http://www.ncbi.nlm.nih.gov/sites/entrez/11532148 PubMed] | ||
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 16:58, 11 June 2009
- Description: hydroxymethylbilane synthase
Gene name | hemC |
Synonyms | |
Essential | no |
Product | hydroxymethylbilane synthase |
Function | heme biosynthesis |
MW, pI | 34 kDa, 5.088 |
Gene length, protein length | 942 bp, 314 aa |
Immediate neighbours | hemD, hemX |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Locus tag: BSU28150
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 4 porphobilinogen + H2O = hydroxymethylbilane + 4 NH3 (according to Swiss-Prot)
- Protein family: HMBS family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: P16616
- KEGG entry: [3]
- E.C. number: 2.5.1.61
Additional information
Expression and regulation
- Operon:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed