Difference between revisions of "FadN"
| Line 35: | Line 35: | ||
=== Basic information === | === Basic information === | ||
| − | * '''Locus tag:''' | + | * '''Locus tag:''' BSU32840 |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
| Line 80: | Line 80: | ||
* '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O32178 O32178] | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/O32178 O32178] | ||
| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+ | + | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu+BSU32840] |
* '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.35 1.1.1.35] | * '''E.C. number:''' [http://www.expasy.org/enzyme/1.1.1.35 1.1.1.35] | ||
Revision as of 13:46, 3 June 2009
- Description: 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA)
| Gene name | fadN |
| Synonyms | yusL |
| Essential | no |
| Product | 3-hydroxyacyl-CoA dehydrogenase (acetoacetyl-CoA) |
| Function | fatty acid degradation |
| MW, pI | 89 kDa, 6.53 |
| Gene length, protein length | 2445 bp, 815 aa |
| Immediate neighbours | fadA, fadM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU32840
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-3-hydroxyacyl-CoA + NAD+ = 3-oxoacyl-CoA + NADH (according to Swiss-Prot)
- Protein family: 3-hydroxyacyl-CoA dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- Swiss prot entry: O32178
- KEGG entry: [3]
- E.C. number: 1.1.1.35
Additional information
Expression and regulation
- Operon:
- Regulation: repressed by glucose (4.5-fold) PubMed
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Blencke et al. (2003) Transcriptional profiling of gene expression in response to glucose in Bacillus subtilis: regulation of the central metabolic pathways. Metab Eng. 5: 133-149 PubMed
- Matsuoka H, Hirooka K, Fujita Y. (2007) Organization and function of the YsiA regulon of Bacillus subtilis involved in fatty acid degradation. J Biol Chem. Feb 23;282(8): 5180-94. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed
