Difference between revisions of "YvrHb"
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− | * '''Description:''' | + | * '''Description:''' two-component response regulator <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
− | |'' | + | |''yvrHb'' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yvrH '' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | + | |style="background:#ABCDEF;" align="center"| '''Essential''' || no |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Product''' || two-component | + | |style="background:#ABCDEF;" align="center"| '''Product''' || two-component response regulator |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || regulation cell surface maintenance | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation cell surface maintenance | ||
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || | + | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26.6 kDa, 5.23 |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || | + | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 714 bp, 237 amino acids |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yvrHa]]'', ''[[yvrG]]'' |
|- | |- | ||
− | | | + | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_nucleotide.txt Gene sequence (+200bp) ]''' |
+ | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]''' | ||
|- | |- | ||
− | + | |colspan="2" | '''Genetic context''' <br/> [[Image:YvrHa_yvrHb_context.GIF]] | |
− | |||
− | |colspan="2" | '''Genetic context''' <br/> [[Image: | ||
− | |||
|- | |- | ||
|} | |} | ||
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=== Basic information === | === Basic information === | ||
− | * ''' | + | * '''Coordinates (CDS):''' |
===Phenotypes of a mutant === | ===Phenotypes of a mutant === | ||
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* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
− | * '''SubtiList entry:''' | + | * '''SubtiList entry:''' no entry |
=== Additional information=== | === Additional information=== | ||
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=== Basic information/ Evolution === | === Basic information/ Evolution === | ||
− | * '''Catalyzed reaction/ biological activity:''' | + | * '''Catalyzed reaction/ biological activity:''' transcription activator [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] |
+ | |||
+ | * '''Protein family:''' OmpR family | ||
+ | |||
+ | * '''Paralogous protein(s):''' | ||
+ | |||
+ | === The YvrHb regulon === | ||
− | + | subject to positive control: ''[[dltA]]-[[dltB]]-[[dltC]]-[[dltD]]-[[dltE]], [[sigX]]-[[rsiX]], [[sunA]], [[sunT]]-[[bdbA]]-[[yolJ]]-[[bdbB]], [[wapA]]-[[yxxG]], [[wprA]], [[yvrI]]-[[yvrHa]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | |
− | + | subject to negative control: ''[[lytA]]-[[lytB]]-[[lytC]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | |
=== Extended information on the protein === | === Extended information on the protein === | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
− | * '''Domains:''' | + | * '''Domains:''' |
− | * '''Modification:''' | + | * '''Modification:''' phosphorylation (Asp) by [[YvrG]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] |
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
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* '''Interactions:''' YvrG-[[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | * '''Interactions:''' YvrG-[[YvrHb]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16306698 PubMed] | ||
− | * '''Localization:''' | + | * '''Localization:''' cytoplasm (according to Swiss-Prot) |
=== Database entries === | === Database entries === | ||
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* '''Structure:''' | * '''Structure:''' | ||
− | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/ | + | * '''Swiss prot entry:''' [http://www.uniprot.org/uniprot/P94504 P94504] |
− | * '''KEGG entry:''' | + | * '''KEGG entry:''' no entry |
* '''E.C. number:''' | * '''E.C. number:''' | ||
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* '''Operon:''' | * '''Operon:''' | ||
− | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 16:05, 2 June 2009
- Description: two-component response regulator
Gene name | yvrHb |
Synonyms | yvrH |
Essential | no |
Product | two-component response regulator |
Function | regulation cell surface maintenance |
MW, pI | 26.6 kDa, 5.23 |
Gene length, protein length | 714 bp, 237 amino acids |
Immediate neighbours | yvrHa, yvrG |
Gene sequence (+200bp) | Protein sequence |
Genetic context |
Contents
The gene
Basic information
- Coordinates (CDS):
Phenotypes of a mutant
unusual autolysis and higher susceptibility to cell envelope antibiotics (bacitracin, aztreonam, cefepime, fosfomycin) PubMed
Database entries
- DBTBS entry: no entry
- SubtiList entry: no entry
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: transcription activator PubMed
- Protein family: OmpR family
- Paralogous protein(s):
The YvrHb regulon
subject to positive control: dltA-dltB-dltC-dltD-dltE, sigX-rsiX, sunA, sunT-bdbA-yolJ-bdbB, wapA-yxxG, wprA, yvrI-yvrHa PubMed
subject to negative control: lytA-lytB-lytC PubMed
Extended information on the protein
- Kinetic information:
- Domains:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- Swiss prot entry: P94504
- KEGG entry: no entry
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
- Serizawa M, Kodama K, Yamamoto H, Kobayashi K, Ogasawara N, Sekiguchi J. (2005) Functional analysis of the YvrGHb two-component system of Bacillus subtilis: identification of the regulated genes by DNA microarray and northern blot analyses. Biosci. Biotechnol. Biochem. 69: 2155-2169. PubMed
- Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed