Difference between revisions of "BkdAA"

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=== Basic information ===
 
=== Basic information ===
  
* '''Coordinates:'''
+
* '''Locus tag:'''
  
 
===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===

Revision as of 14:28, 2 June 2009

  • Description: 2-oxoisovalerate dehydrogenase (E1 alpha subunit)

Gene name bkdAA
Synonyms bfmBAA, bfmB1a, bkd
Essential no
Product 2-oxoisovalerate dehydrogenase (E1 alpha subunit)

(2-oxoisovalerate dehydrogenase alpha subunit) (EC 1.2.4.4)

Function utilization of branched-chain keto acids
MW, pI 36 kDa, 4.778
Gene length, protein length 990 bp, 330 aa
Immediate neighbours bkdAB, lpdV
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
BkdAA context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag:

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 3-methyl-2-oxobutanoate + [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] lipoyllysine = [dihydrolipoyllysine-residue (2-methylpropanoyl)transferase] S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 (according to Swiss-Prot)
  • Protein family: BCKDHA family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: Membrane-proximal (Spotty) PubMed

Database entries

  • Structure:
  • Swiss prot entry:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References


  1. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed