GTP-binding proteins

Parent category	6. Groups of genes
Neighbouring categories	6.1. Essential genes 6.2. Membrane proteins 6.3. GTP-binding proteins 6.4. Phosphoproteins 6.5. Universally conserved proteins 6.6. Poorly characterized/ putative enzymes 6.7. Proteins of unknown function 6.8. Short peptides 6.9. ncRNA 6.10. Pseudogenes
Related categories	translation
Overview on the categories (Excel file) All genes and their categories (Excel file)

Genes in this functional category

• cpgA
• engA
• era
• lepA
• obg
• rbgA
• thdF
• ynbA
• yqeH
• ysxC
• yyaF

Additional information

• several GTP-binding proteins bind ppGpp resulting in inhibition of ther GTPase activity PubMed

Important publications

Brett Thurlow, Joseph H Davis, Vivian Leong, Trevor F Moraes, James R Williamson, Joaquin Ortega
Binding properties of YjeQ (RsgA), RbfA, RimM and Era to assembly intermediates of the 30S subunit.
Nucleic Acids Res: 2016, 44(20);9918-9932
[PubMed:27382067] [WorldCat.org] [DOI] (I p)

Rebecca M Corrigan, Lauren E Bellows, Alison Wood, Angelika Gründling
ppGpp negatively impacts ribosome assembly affecting growth and antimicrobial tolerance in Gram-positive bacteria.
Proc Natl Acad Sci U S A: 2016, 113(12);E1710-9
[PubMed:26951678] [WorldCat.org] [DOI] (I p)

Natalie Verstraeten, Maarten Fauvart, Wim Versées, Jan Michiels
The universally conserved prokaryotic GTPases.
Microbiol Mol Biol Rev: 2011, 75(3);507-42, second and third pages of table of contents
[PubMed:21885683] [WorldCat.org] [DOI] (I p)

Robert A Britton
Role of GTPases in bacterial ribosome assembly.
Annu Rev Microbiol: 2009, 63;155-76
[PubMed:19575570] [WorldCat.org] [DOI] (I p)

Takuya Morimoto, Pek Chin Loh, Tomohiro Hirai, Kei Asai, Kazuo Kobayashi, Shigeki Moriya, Naotake Ogasawara
Six GTP-binding proteins of the Era/Obg family are essential for cell growth in Bacillus subtilis.
Microbiology (Reading): 2002, 148(Pt 11);3539-3552
[PubMed:12427945] [WorldCat.org] [DOI] (P p)