Difference between revisions of "TuaB"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* slow growth {{PubMed|25918422}}
 +
* severe cell shape defect {{PubMed|25918422}}
  
 
=== Database entries ===
 
=== Database entries ===
Line 138: Line 140:
 
=References=
 
=References=
  
<pubmed>9611818,10048024 10627039 </pubmed>
+
<pubmed>9611818,10048024 10627039 25918422 12603313</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 12:54, 8 May 2015

  • Description: polymer export

Gene name tuaB
Synonyms yvhB
Essential no
Product unknown
Function biosynthesis of teichuronic acid
Gene expression levels in SubtiExpress: tuaB
MW, pI 53 kDa, 9.984
Gene length, protein length 1449 bp, 483 aa
Immediate neighbours tuaC, tuaA/1
Sequences Protein DNA DNA_with_flanks
Genetic context
TuaB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
TuaB expression.png















Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components, membrane proteins

This gene is a member of the following regulons

PhoP regulon

The gene

Basic information

  • Locus tag: BSU35600

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • expressed under conditions of phosphate limitation (PhoP) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Alexander J Meeske, Lok-To Sham, Harvey Kimsey, Byoung-Mo Koo, Carol A Gross, Thomas G Bernhardt, David Z Rudner
MurJ and a novel lipid II flippase are required for cell wall biogenesis in Bacillus subtilis.
Proc Natl Acad Sci U S A: 2015, 112(20);6437-42
[PubMed:25918422] [WorldCat.org] [DOI] (I p)

Rikki N Hvorup, Brit Winnen, Abraham B Chang, Yong Jiang, Xiao-Feng Zhou, Milton H Saier
The multidrug/oligosaccharidyl-lipid/polysaccharide (MOP) exporter superfamily.
Eur J Biochem: 2003, 270(5);799-813
[PubMed:12603313] [WorldCat.org] [DOI] (P p)

Maryam Lahooti, Colin R Harwood
Transcriptional analysis of the Bacillus subtilis teichuronic acid operon.
Microbiology (Reading): 1999, 145 ( Pt 12);3409-3417
[PubMed:10627039] [WorldCat.org] [DOI] (P p)

B Soldo, V Lazarevic, M Pagni, D Karamata
Teichuronic acid operon of Bacillus subtilis 168.
Mol Microbiol: 1999, 31(3);795-805
[PubMed:10048024] [WorldCat.org] [DOI] (P p)

Wei Liu, F Marion Hulett
Comparison of PhoP binding to the tuaA promoter with PhoP binding to other Pho-regulon promoters establishes a Bacillus subtilis Pho core binding site.
Microbiology (Reading): 1998, 144 ( Pt 5);1443-1450
[PubMed:9611818] [WorldCat.org] [DOI] (P p)