Difference between revisions of "BpsA"
| Line 62: | Line 62: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| Line 111: | Line 109: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcsA_2316956_2318053_-1 bpsA] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=bcsA_2316956_2318053_-1 bpsA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' |
* '''Regulation:''' | * '''Regulation:''' | ||
| Line 121: | Line 119: | ||
=Biological materials = | =Biological materials = | ||
| − | * '''Mutant:''' | + | * '''Mutant:''' BKE22050 (''[[bpsA]]''::''erm'', available in the BGSC and in [[Jörg Stülke]]'s lab) |
* '''Expression vector:''' | * '''Expression vector:''' | ||
Revision as of 18:48, 1 February 2015
- Description: type III polyketide synthase
| Gene name | bpsA |
| Synonyms | bcsA |
| Essential | no |
| Product | type III polyketide synthase |
| Function | polyketide synthesis |
| Gene expression levels in SubtiExpress: bpsA | |
| MW, pI | 40 kDa, 7.958 |
| Gene length, protein length | 1095 bp, 365 aa |
| Immediate neighbours | bpsB, pbuX |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, membrane proteins, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22050
Phenotypes of a mutant
Database entries
- BsubCyc: BSU22050
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: synthesis of triketide pyrones from long-chain fatty acyl CoA thioesters as starter substrates and malonyl-CoA as an extender substrate PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU22050
- Structure:
- UniProt: P54157
- KEGG entry: [2]
- E.C. number: 2.3.1.74
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: BKE22050 (bpsA::erm, available in the BGSC and in Jörg Stülke's lab)
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Chiaki Nakano, Hiroki Ozawa, Genki Akanuma, Nobutaka Funa, Sueharu Horinouchi
Biosynthesis of aliphatic polyketides by type III polyketide synthase and methyltransferase in Bacillus subtilis.
J Bacteriol: 2009, 191(15);4916-23
[PubMed:19465653]
[WorldCat.org]
[DOI]
(I p)
