CitR

• Description: transcriptional repressor of citA
  
  

Gene name	citR
Synonyms
Essential	no
Product	transcriptional repressor (LysR family)
Function	regulation of the minor citrate synthase
Gene expression levels in SubtiExpress: citR
Regulatory function of this protein in SubtiPathways: citR
Metabolic function and regulation of this protein in SubtiPathways: CitR
MW, pI	35 kDa, 8.67
Gene length, protein length	924 bp, 308 aa
Immediate neighbours	lytE, citA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

transcription factors and their control

The CitR regulon:

• citA

The gene

Basic information

• Locus tag: BSU09430

Database entries

• BsubCyc: BSU09430

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LysR family

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• BsubCyc: BSU09430

• Structure:

• UniProt: P39127

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: citR PubMed

• Expression browser: citR PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:
  • GP1283 (citA::aphA3), available in Jörg Stülke's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

S Jin, A L Sonenshein
Transcriptional regulation of Bacillus subtilis citrate synthase genes.
J Bacteriol: 1994, 176(15);4680-90
[PubMed:8045899] [WorldCat.org] [DOI] (P p)

S Jin, A L Sonenshein
Identification of two distinct Bacillus subtilis citrate synthase genes.
J Bacteriol: 1994, 176(15);4669-79
[PubMed:8045898] [WorldCat.org] [DOI] (P p)