Difference between revisions of "HolB"
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[ | + | * '''Operon:''' ''[[darA]]-[[yaaR]]-[[holB]]-[[yaaT]]-[[yabA]]-[[yabB]]-[[yazA]]-[[yabC]]'' {{PubMed|22383849}} |
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=holB_40665_41654_1 holB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=holB_40665_41654_1 holB] {{PubMed|22383849}} |
Revision as of 12:58, 10 November 2014
- Description: DNA polymerase III (delta' subunit), part of the clamp-loader complex and the replisome
Gene name | holB |
Synonyms | yaaS |
Essential | yes PubMed |
Product | DNA polymerase III (delta' subunit) |
Function | DNA replication |
Gene expression levels in SubtiExpress: holB | |
Interactions involving this protein in SubtInteract: HolB | |
MW, pI | 37 kDa, 6.334 |
Gene length, protein length | 987 bp, 329 aa |
Immediate neighbours | yaaR, yaaT |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
DNA replication, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00310
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU00310
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1) (according to Swiss-Prot)
- required for bacteriophage SPP1 replication PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU00310
- Structure:
- UniProt: P37540
- KEGG entry: [2]
- E.C. number: 2.7.7.7
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References