Difference between revisions of "CueR"
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| − | * '''Description:''' transcriptional regulator of the ''[[copZ]]-[[copA]]'' operon <br/><br/> | + | * '''Description:''' transcriptional regulator ([[MerR family]]) of the ''[[copZ]]-[[copA]]'' operon <br/><br/> |
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
| − | * '''Protein family:''' | + | * '''Protein family:''' [[MerR family]] |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Revision as of 13:17, 22 June 2014
- Description: transcriptional regulator (MerR family) of the copZ-copA operon
| Gene name | cueR |
| Synonyms | yhdQ |
| Essential | no |
| Product | transcriptional regulator (MerR family) |
| Function | regulation of the copZ-copA operon |
| Gene expression levels in SubtiExpress: cueR | |
| Metabolic function and regulation of this protein in SubtiPathways: metal ion homeostasis | |
| MW, pI | 16 kDa, 7.886 |
| Gene length, protein length | 429 bp, 143 aa |
| Immediate neighbours | yhdP, yhdR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), transcription factors and their control, resistance against toxic metals
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU09560
Phenotypes of a mutant
Database entries
- BsubCyc: BSU09560
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: MerR family
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU09560
- Structure:
- UniProt: O07586
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Nesha May Andoy, Susanta K Sarkar, Qi Wang, Debashis Panda, Jaime J Benítez, Aleksandr Kalininskiy, Peng Chen
Single-molecule study of metalloregulator CueR-DNA interactions using engineered Holliday junctions.
Biophys J: 2009, 97(3);844-52
[PubMed:19651042]
[WorldCat.org]
[DOI]
(I p)
Gregory T Smaldone, John D Helmann
CsoR regulates the copper efflux operon copZA in Bacillus subtilis.
Microbiology (Reading): 2007, 153(Pt 12);4123-4128
[PubMed:18048925]
[WorldCat.org]
[DOI]
(P p)
Charles M Moore, Ahmed Gaballa, Monica Hui, Rick W Ye, John D Helmann
Genetic and physiological responses of Bacillus subtilis to metal ion stress.
Mol Microbiol: 2005, 57(1);27-40
[PubMed:15948947]
[WorldCat.org]
[DOI]
(P p)
Ahmed Gaballa, Min Cao, John D Helmann
Two MerR homologues that affect copper induction of the Bacillus subtilis copZA operon.
Microbiology (Reading): 2003, 149(Pt 12);3413-3421
[PubMed:14663075]
[WorldCat.org]
[DOI]
(P p)
