Difference between revisions of "SpoIIE"
Line 45: | Line 45: | ||
{{SubtiWiki category|[[sigma factors and their control]]}}, | {{SubtiWiki category|[[sigma factors and their control]]}}, | ||
{{SubtiWiki category|[[membrane proteins]]}}, | {{SubtiWiki category|[[membrane proteins]]}}, | ||
− | {{SubtiWiki category|[[ | + | {{SubtiWiki category|[[sporulation proteins]]}} |
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = |
Revision as of 12:55, 24 April 2014
- Description: protein serine phosphatase, septum-associated PP2C, dephosphorylation of SpoIIAA
Gene name | spoIIE |
Synonyms | spoIIH, spoIIK |
Essential | no |
Product | protein serine phosphatase, septum-associated PP2C |
Function | control of SigF activity required for normal formation of the asymmetric septum |
Gene expression levels in SubtiExpress: spoIIE | |
Interactions involving this protein in SubtInteract: SpoIIE | |
Metabolic function and regulation of this protein in SubtiPathways: spoIIE | |
MW, pI | 91 kDa, 6.137 |
Gene length, protein length | 2481 bp, 827 aa |
Immediate neighbours | trnSL-Glu1, yabS |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
protein modification, sigma factors and their control, membrane proteins, sporulation proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00640
Phenotypes of a mutant
Database entries
- BsubCyc: BSU00640
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: dephosphorylation of SpoIIAA
- Protein family: PP2C phosphatase
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- cell membrane (according to Swiss-Prot)
- localizes to the polar cell division sites where it causes FtsZ to relocate from mid-cell to form polar Z-rings
Database entries
- BsubCyc: BSU00640
- KEGG entry: [3]
- E.C. number: 3.1.3.16
Additional information
Expression and regulation
- Operon: spoIIE (DBTBS)
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Imrich Barak, Slovak Academy of Science, Bratislava, Slovakia homepage
Your additional remarks
References
Modeling of SigF activation
Georgios Fengos, Dagmar Iber
Prediction stability in a data-based, mechanistic model of σF regulation during sporulation in Bacillus subtilis.
Sci Rep: 2013, 3;2755
[PubMed:24067622]
[WorldCat.org]
[DOI]
(I e)
Dagmar Iber
Inferring Biological Mechanisms by Data-Based Mathematical Modelling: Compartment-Specific Gene Activation during Sporulation in Bacillus subtilis as a Test Case.
Adv Bioinformatics: 2011, 2011;124062
[PubMed:22312331]
[WorldCat.org]
[DOI]
(I p)
Original Publications