yerA

yerA
168

N6-methyladenosine deaminase

Locus
BSU_06560
Molecular weight
66.47 kDa
Isoelectric point
5.82
Protein length
580 aaSequenceBlast
Gene length
1743 bpSequenceBlast
Function
utilization of N6-methyladenosine
Product
N6-methyladenosine deaminase
Essential
no
E.C.
3.5.4.2
Synonyms
yerA
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG1001 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
713,664 → 715,406
The protein
Catalyzed reaction/ biological activity
N6-methyladenosine --> inosine +NH3PubMed
Protein family
Metallo-dependent hydrolases superfamily (according to UniProt)
Cofactors
Mn2+ PubMed
Structure
9JQL (PDB) (C-terminal domain, aa 380 ... 580) PubMed
O34909 (AlphaFold)
Modification
phosphorylation on Ser-399 PubMed
Expression and Regulation
Operons
Genes
yerA-yerB-yerC
Description
PubMed
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yerA->yerC

2025-04-04 03:17:12

Jstuelk

105

27118e8ac25de79a5f16b7c892f0bef97db8a276

FB076D59B31BC86C730E1BA088BDB513FF318277

Biological materials
Mutant
MGNA-A910 (yerA::erm), available at the NBRP B. subtilis, Japan
BKE06560 (ΔyerA::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCACATACTCTCCTTTA,  downstream forward: _UP4_TAAAATATAAAAGAGCAGGG
BKK06560 (ΔyerA::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CATTCACATACTCTCCTTTA,  downstream forward: _UP4_TAAAATATAAAAGAGCAGGG
References
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Time of last update: 2025-04-03 14:58:59

Author of last update: Jstuelk