Difference between revisions of "AroD"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25660&redirect=T BSU25660] | ||
* '''DBTBS entry:''' no entry | * '''DBTBS entry:''' no entry | ||
| Line 91: | Line 92: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU25660&redirect=T BSU25660] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2HK8 2HK8] (from ''Aquifex aeolicus'', 42% identity, 61% similarity) {{PubMed|17649975}} | * '''Structure:''' [http://www.rcsb.org/pdb/cgi/explore.cgi?pdbId=2HK8 2HK8] (from ''Aquifex aeolicus'', 42% identity, 61% similarity) {{PubMed|17649975}} | ||
Revision as of 14:16, 2 April 2014
- Description: shikimate dehydrogenase
| Gene name | aroD |
| Synonyms | |
| Essential | no |
| Product | shikimate dehydrogenase |
| Function | biosynthesis of aromatic amino acids |
| Gene expression levels in SubtiExpress: aroD | |
| Metabolic function and regulation of this protein in SubtiPathways: aroD | |
| MW, pI | 30 kDa, 6.077 |
| Gene length, protein length | 840 bp, 280 aa |
| Immediate neighbours | yqeI, yqeH |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU25660
Phenotypes of a mutant
Database entries
- BsubCyc: BSU25660
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Shikimate + NADP+ = 3-dehydroshikimate + NADPH (according to Swiss-Prot)
- Protein family: shikimate dehydrogenase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU25660
- UniProt: P54374
- KEGG entry: [2]
- E.C. number: 1.1.1.25
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dong-Feng Liu, Guo-Min Ai, Qing-Xiang Zheng, Chang Liu, Cheng-Ying Jiang, Li-Xia Liu, Bo Zhang, Yi-Ming Liu, Chen Yang, Shuang-Jiang Liu
Metabolic flux responses to genetic modification for shikimic acid production by Bacillus subtilis strains.
Microb Cell Fact: 2014, 13(1);40
[PubMed:24628944]
[WorldCat.org]
[DOI]
(I e)
J Bergsma, K E Meihuizen, W Van Oeveren, W N Konings
Restoration of NADH oxidation with menaquinones and menaquinone analogues in membrane vesicles from the menaquinone-deficient Bacillus subtilis aroD.
Eur J Biochem: 1982, 125(3);651-7
[PubMed:6811271]
[WorldCat.org]
[DOI]
(P p)
