CtaB

• Description: heme O synthase (major enzyme)
  
  

Gene name	ctaB
Synonyms
Essential	no
Product	heme O synthase (major enzyme)
Function	heme biosynthesis
Gene expression levels in SubtiExpress: ctaB
MW, pI	33 kDa, 9.566
Gene length, protein length	915 bp, 305 aa
Immediate neighbours	ctaA, ctaC
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biosynthesis of cofactors, membrane proteins

This gene is a member of the following regulons

ResD regulon

The gene

Basic information

• Locus tag: BSU14880

Database entries

• BsubCyc: BSU14880

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: ubiA prenyltransferase family, Protoheme IX farnesyltransferase subfamily (according to Swiss-Prot)

• Paralogous protein(s): CtaO

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot)

Database entries

• BsubCyc: BSU14880

• Structure:

• UniProt: P24009

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: ctaB-ctaC-ctaD-ctaE-ctaF-ctaG PubMed

• Expression browser: ctaB PubMed

• Sigma factor:

• Regulation:
  • expressed under anaerobic conditions (ResD) PubMed

• Regulatory mechanism:
  • ResD: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: