NagP

• Description: N-acetylglucosamine-specific phosphotransferase system, EIICB of the PTS
  
  

Gene name	nagP
Synonyms	yflF
Essential	no
Product	N-acetylglucosamine-specific PTS, EIICB
Function	N-acetylglucosamine uptake and phosphorylation
Gene expression levels in SubtiExpress: nagP
Metabolic function and regulation of this protein in SubtiPathways: nagP
MW, pI	48 kDa, 7.127
Gene length, protein length	1356 bp, 452 aa
Immediate neighbours	yflG, ltaS
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, membrane proteins, phosphoproteins

This gene is a member of the following regulons

NagR regulon

The gene

Basic information

• Locus tag: BSU07700

Phenotypes of a mutant

• no growth on N-acetylglucosamine PubMed

Database entries

• BsubCyc: BSU07700

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: Protein EIIB N(pi)-phospho-L-histidine/cysteine + sugar = protein EIIB + sugar phosphate (according to Swiss-Prot)

• Protein family: PTS permease, glucose permease (Glc) family PubMed

• Paralogous protein(s): GamP

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cell membrane (according to Swiss-Prot), membrane associated PubMed

Database entries

• BsubCyc: BSU07700

• Structure:

• UniProt: O34521

• KEGG entry: [2]

• E.C. number: 2.7.1.69

Expression and regulation

• Operon: nagP PubMed

• Expression browser: nagP PubMed

• Sigma factor: SigA PubMed

• Regulation:
  • induced in the presence of N-acetylglucosamine (NagR) PubMed

• Regulatory mechanism:
  • NagR: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: