Difference between revisions of "PurB"
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=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06440&redirect=T BSU06440] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/purEKBCSQLFMNHD.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/purEKBCSQLFMNHD.html] | ||
Line 89: | Line 90: | ||
=== Database entries === | === Database entries === | ||
+ | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU06440&redirect=T BSU06440] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1F1O 1F1O] | * '''Structure:''' [http://www.rcsb.org/pdb/explore.do?structureId=1F1O 1F1O] |
Revision as of 13:07, 2 April 2014
- Description: adenylsuccinate lyase
Gene name | purB |
Synonyms | |
Essential | no |
Product | adenylsuccinate lyase |
Function | purine biosynthesis |
Gene expression levels in SubtiExpress: purB | |
Metabolic function and regulation of this protein in SubtiPathways: purB | |
MW, pI | 49 kDa, 5.822 |
Gene length, protein length | 1293 bp, 431 aa |
Immediate neighbours | purK, purC |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis/ acquisition of nucleotides, most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU06440
Phenotypes of a mutant
Database entries
- BsubCyc: BSU06440
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: N(6)-(1,2-dicarboxyethyl)AMP = fumarate + AMP (according to Swiss-Prot)
- Protein family: Adenylosuccinate lyase subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU06440
- Structure: 1F1O
- UniProt: P12047
- KEGG entry: [3]
- E.C. number: 4.3.2.2
Additional information
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- subject to Clp-dependent proteolysis upon glucose starvation PubMed
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References