Difference between revisions of "GamR"
Line 83: | Line 83: | ||
* '''[[Cofactors]]:''' | * '''[[Cofactors]]:''' | ||
− | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' |
+ | ** glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the ''[[gamA]]-[[gamP]]'' and ''[[gamR]]-[[ybgB]]'' operons {{PubMed|24673833}} | ||
* '''[[SubtInteract|Interactions]]:''' | * '''[[SubtInteract|Interactions]]:''' | ||
Line 110: | Line 111: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
− | ** induced by glucosamine ([[GamR]]) {{PubMed|23667565}} | + | ** induced by glucosamine ([[GamR]]) {{PubMed|24673833,23667565}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | ** [[GamR]]: transcription repression {{PubMed|23667565}} | + | ** [[GamR]]: transcription repression {{PubMed|24673833,23667565}} |
* '''Additional information:''' | * '''Additional information:''' |
Revision as of 10:56, 31 March 2014
- Description: transcriptional repressor (GntR family) of the gamA-gamP operon
Gene name | gamR |
Synonyms | ybgA |
Essential | no |
Product | transcriptional regulator (GntR family) |
Function | regulation of glucosamine utilization |
Gene expression levels in SubtiExpress: gamR | |
MW, pI | 26 kDa, 5.559 |
Gene length, protein length | 705 bp, 235 aa |
Immediate neighbours | gamA, ybgB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The GamR regulon:
The gene
Basic information
- Locus tag: BSU02370
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: GntR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31459
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References