Difference between revisions of "GamR"

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* '''[[Cofactors]]:'''
 
* '''[[Cofactors]]:'''
  
* '''Effectors of protein activity:'''
+
* '''Effectors of protein activity:'''  
 +
** glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the ''[[gamA]]-[[gamP]]'' and ''[[gamR]]-[[ybgB]]''  operons {{PubMed|24673833}}
  
 
* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
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* '''Regulation:'''  
 
* '''Regulation:'''  
** induced by glucosamine ([[GamR]]) {{PubMed|23667565}}  
+
** induced by glucosamine ([[GamR]]) {{PubMed|24673833,23667565}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** [[GamR]]: transcription repression {{PubMed|23667565}}  
+
** [[GamR]]: transcription repression {{PubMed|24673833,23667565}}  
  
 
* '''Additional information:'''
 
* '''Additional information:'''

Revision as of 10:56, 31 March 2014

Gene name gamR
Synonyms ybgA
Essential no
Product transcriptional regulator (GntR family)
Function regulation of glucosamine utilization
Gene expression levels in SubtiExpress: gamR
MW, pI 26 kDa, 5.559
Gene length, protein length 705 bp, 235 aa
Immediate neighbours gamA, ybgB
Sequences Protein DNA DNA_with_flanks
Genetic context
YbgA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YbgA expression.png















Categories containing this gene/protein

cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control

This gene is a member of the following regulons

GamR regulon

The GamR regulon:

The gene

Basic information

  • Locus tag: BSU02370

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:
    • glucosamine-6-phosphate acts as molecular inducer that prevents GamR from binding to its operator sites in the promoter regions of the gamA-gamP and gamR-ybgB operons PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References