Difference between revisions of "GamR"
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|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
− | |'' | + | |''gamR'' |
|- | |- | ||
− | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''ybgA '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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|style="background:#ABCDEF;" align="center"|'''Function''' || regulation of glucosamine utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || regulation of glucosamine utilization | ||
|- | |- | ||
− | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02370 | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU02370 gamR] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.559 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 26 kDa, 5.559 | ||
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= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
− | {{SubtiWiki regulon|[[ | + | {{SubtiWiki regulon|[[GamR regulon]]}} |
− | = The [[ | + | = The [[GamR regulon]]: = |
− | * ''[[gamA]]-[[gamP]]'', ''[[ | + | * ''[[gamA]]-[[gamP]]'', ''[[gamR]]-[[ybgB]]'' |
=The gene= | =The gene= | ||
Line 62: | Line 62: | ||
=== Additional information=== | === Additional information=== | ||
− | |||
− | |||
− | |||
=The protein= | =The protein= | ||
Line 72: | Line 69: | ||
* '''Catalyzed reaction/ biological activity:''' | * '''Catalyzed reaction/ biological activity:''' | ||
− | * '''Protein family:''' | + | * '''Protein family:''' [[GntR family]] of transcription factors |
* '''Paralogous protein(s):''' | * '''Paralogous protein(s):''' | ||
Line 80: | Line 77: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
− | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
− | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
Line 106: | Line 103: | ||
=Expression and regulation= | =Expression and regulation= | ||
− | * '''Operon:''' ''[[ | + | * '''Operon:''' ''[[gamR]]-[[ybgB]]'' {{PubMed|23667565}} |
− | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybgA_257791_258498_1 | + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ybgA_257791_258498_1 gamR] {{PubMed|22383849}} |
* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23667565}} | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|23667565}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
− | ** induced by glucosamine ([[ | + | ** induced by glucosamine ([[GamR]]) {{PubMed|23667565}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
− | ** [[ | + | ** [[GamR]]: transcription repression {{PubMed|23667565}} |
* '''Additional information:''' | * '''Additional information:''' | ||
Line 139: | Line 136: | ||
=References= | =References= | ||
− | <pubmed> 10627040 23667565 </pubmed> | + | <pubmed> 10627040 23667565 24673833 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 07:39, 31 March 2014
- Description: transcriptional repressor (GntR family) of the gamA-gamP operon
Gene name | gamR |
Synonyms | ybgA |
Essential | no |
Product | transcriptional regulator (GntR family) |
Function | regulation of glucosamine utilization |
Gene expression levels in SubtiExpress: gamR | |
MW, pI | 26 kDa, 5.559 |
Gene length, protein length | 705 bp, 235 aa |
Immediate neighbours | gamA, ybgB |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell wall degradation/ turnover, utilization of specific carbon sources, transcription factors and their control
This gene is a member of the following regulons
The GamR regulon:
The gene
Basic information
- Locus tag: BSU02370
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: GntR family of transcription factors
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O31459
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Isabelle Gaugué, Jacques Oberto, Jacqueline Plumbridge
Regulation of amino sugar utilization in Bacillus subtilis by the GntR family regulators, NagR and GamR.
Mol Microbiol: 2014, 92(1);100-15
[PubMed:24673833]
[WorldCat.org]
[DOI]
(I p)
Isabelle Gaugué, Jacques Oberto, Harald Putzer, Jacqueline Plumbridge
The use of amino sugars by Bacillus subtilis: presence of a unique operon for the catabolism of glucosamine.
PLoS One: 2013, 8(5);e63025
[PubMed:23667565]
[WorldCat.org]
[DOI]
(I e)
Jonathan Reizer, Steffi Bachem, Aiala Reizer, Maryvonne Arnaud, Milton H Saier, Jörg Stülke
Novel phosphotransferase system genes revealed by genome analysis - the complete complement of PTS proteins encoded within the genome of Bacillus subtilis.
Microbiology (Reading): 1999, 145 ( Pt 12);3419-3429
[PubMed:10627040]
[WorldCat.org]
[DOI]
(P p)