Difference between revisions of "CitG"

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= [[Categories]] containing this gene/protein =
 
= [[Categories]] containing this gene/protein =
{{SubtiWiki category|[[carbon core metabolism]]}}
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{{SubtiWiki category|[[carbon core metabolism]]}},
 +
[[most abundant proteins]]
  
 
= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fumC_3389024_3390412_-1 citG] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fumC_3389024_3390412_-1 citG] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigA]] {{PubMed|3130545,2509422,2509423}}, [[SigH]] {{PubMed|3130545,2509422}}
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* '''[[Sigma factor]]:''' [[SigA]] {{PubMed|3130545,2509422,2509423}}, [[SigH]] {{PubMed|3130545,2509422}}
  
 
* '''Regulation:''' constitutive
 
* '''Regulation:''' constitutive
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* '''Additional information:'''
 
* '''Additional information:'''
 +
** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}}
  
 
=Biological materials =
 
=Biological materials =
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=References=
 
=References=
'''Additional publications:''' {{PubMed|21661762}}
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<pubmed>2509422,3923430 ,3130545 2509423 20933603</pubmed>
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<pubmed>2509422,3923430 ,3130545 2509423 21661762 20933603 15378759</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:40, 5 March 2014

  • Description: fumarase

Gene name citG
Synonyms
Essential no
Product fumarate hydratase
Function TCA cycle
Gene expression levels in SubtiExpress: citG
Interactions involving this protein in SubtInteract: CitG
Metabolic function and regulation of this protein in SubtiPathways:
citG
MW, pI 50 kDa, 5.475
Gene length, protein length 1386 bp, 462 aa
Immediate neighbours yuxN, yvzF
Sequences Protein DNA DNA_with_flanks
Genetic context
CitG context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CitG expression.png















Categories containing this gene/protein

carbon core metabolism, most abundant proteins

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU33040

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: (S)-malate = fumarate + H2O (according to Swiss-Prot)
  • Protein family: Fumarase subfamily (according to Swiss-Prot)
  • Paralogous protein(s): AnsB

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure: 3R6Q (aspartase from Bacillus sp. YM55-1, 43% identity, 77% similarity) PubMed
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation: constitutive
  • Regulatory mechanism:

Biological materials

  • Expression vector:
  • GFP fusion: GP1433 (spc, based on pGP1870), available in the Stülke lab
  • two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Jörg Stülke's lab
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References