Difference between revisions of "MtrB"
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<br/><br/><br/><br/> | <br/><br/><br/><br/> | ||
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= [[Categories]] containing this gene/protein = | = [[Categories]] containing this gene/protein = | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mtrB_2384534_2384761_-1 mtrB] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mtrB_2384534_2384761_-1 mtrB] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|2123343}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|2123343}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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==Original Publications== | ==Original Publications== | ||
| − | <pubmed> 22970197 19033375, 17881743 10660627 10714985 12963367 14702295 16879415 17114058 17114263 11805104,7525975,10735881,15262953,14976255,8647825,18334255,10499579,7715723,8932308,11214184,15743934,7515880,9242649,7759487,15050822,14687568,9245598,9765233,11914485,15099736,7678334,8643393,15588817,16738132,1551827,17555767,7544009,11786553,11566976,2123343,11557884,12133840,16784236,10369778,7715723 10499579 11566976 7515880, 21097886 21984911 </pubmed> | + | <pubmed> 22970197 19033375, 17881743 10660627 10714985 12963367 14702295 16879415 17114058 17114263 11805104,7525975,10735881,15262953,14976255,8647825,18334255,10499579,7715723,8932308,11214184,15743934,7515880,9242649,7759487,15050822,14687568,9245598,9765233,11914485,15099736,7678334,8643393,15588817,16738132,1551827,17555767,7544009,11786553,11566976,2123343,11557884,12133840,16784236,10369778,7715723 10499579 11566976 7515880, 21097886 21984911 24505391 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:30, 9 February 2014
- Description: tryptophan operon RNA-binding attenuation protein (TRAP), controls the RNA switch in front of genes involved in biosynthesis and acquisition of tryptophan
| Gene name | mtrB |
| Synonyms | |
| Essential | no |
| Product | tryptophan operon RNA-binding attenuation protein (TRAP) |
| Function | regulation of tryptophan biosynthesis (and translation) attenuation in the trp operon; repression of the folate operon |
| Gene expression levels in SubtiExpress: mtrB | |
| Interactions involving this protein in SubtInteract: TRAP | |
| Metabolic function and regulation of this protein in SubtiPathways: mtrB | |
| MW, pI | 8 kDa, 7.333 |
| Gene length, protein length | 225 bp, 75 aa |
| Immediate neighbours | hepS, folE |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
biosynthesis/ acquisition of amino acids, transcription factors and their control, RNA binding regulators
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU22770
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: prpD family (according to Swiss-Prot)
- Paralogous protein(s):
Genes controlled by MtrB
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- binding of tryptophan results RNA binding and thus in transcription termination
Database entries
- UniProt: P19466
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Original Publications
