Difference between revisions of "GlpQ"
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=== Additional information=== | === Additional information=== | ||
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=The protein= | =The protein= | ||
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* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=glpQ_233014_233895_-1 glpQ] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=glpQ_233014_233895_-1 glpQ] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigA]] {{PubMed|8012593}} | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8012593}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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=References= | =References= | ||
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| + | <pubmed>24373430 </pubmed> | ||
| + | == Original publications == | ||
<pubmed>8012593,10913081, 18214974,18957862, </pubmed> | <pubmed>8012593,10913081, 18214974,18957862, </pubmed> | ||
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[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 12:43, 28 January 2014
- Description: glycerolphosphate diester phosphodiesterase
| Gene name | glpQ |
| Synonyms | ybeD |
| Essential | no |
| Product | glycerolphosphate diester phosphodiesterase |
| Function | glycerol-3-phosphate utilization |
| Gene expression levels in SubtiExpress: glpQ | |
| MW, pI | 32 kDa, 9.263 |
| Gene length, protein length | 879 bp, 293 aa |
| Immediate neighbours | ybeC, glpT |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
utilization of specific carbon sources, utilization of lipids
This gene is a member of the following regulons
CcpA regulon, GlpP regulon, PhoP regulon
The gene
Basic information
- Locus tag: BSU02130
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: A glycerophosphodiester + H2O = an alcohol + sn-glycerol 3-phosphate (according to Swiss-Prot)
- Protein family: glycerophosphoryl diester phosphodiesterase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization:
- extracellular (signal peptide) PubMed
Database entries
- UniProt: P37965
- KEGG entry: [3]
- E.C. number: 3.1.4.46
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- CcpA: transcription repression
- GlpP: transcriptional antitermination via a protein-dependent RNA switch
- PhoP: transcription activation PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Daniela Corda, Maria G Mosca, Noriyasu Ohshima, Laura Grauso, Noriyuki Yanaka, Stefania Mariggiò
The emerging physiological roles of the glycerophosphodiesterase family.
FEBS J: 2014, 281(4);998-1016
[PubMed:24373430]
[WorldCat.org]
[DOI]
(I p)
Original publications
Birgit Voigt, Haike Antelmann, Dirk Albrecht, Armin Ehrenreich, Karl-Heinz Maurer, Stefan Evers, Gerhard Gottschalk, Jan Maarten van Dijl, Thomas Schweder, Michael Hecker
Cell physiology and protein secretion of Bacillus licheniformis compared to Bacillus subtilis.
J Mol Microbiol Biotechnol: 2009, 16(1-2);53-68
[PubMed:18957862]
[WorldCat.org]
[DOI]
(I p)
Liang Shi, Jun-Feng Liu, Xiao-Min An, Dong-Cai Liang
Crystal structure of glycerophosphodiester phosphodiesterase (GDPD) from Thermoanaerobacter tengcongensis, a metal ion-dependent enzyme: insight into the catalytic mechanism.
Proteins: 2008, 72(1);280-8
[PubMed:18214974]
[WorldCat.org]
[DOI]
(I p)
H Antelmann, C Scharf, M Hecker
Phosphate starvation-inducible proteins of Bacillus subtilis: proteomics and transcriptional analysis.
J Bacteriol: 2000, 182(16);4478-90
[PubMed:10913081]
[WorldCat.org]
[DOI]
(P p)
R P Nilsson, L Beijer, B Rutberg
The glpT and glpQ genes of the glycerol regulon in Bacillus subtilis.
Microbiology (Reading): 1994, 140 ( Pt 4);723-30
[PubMed:8012593]
[WorldCat.org]
[DOI]
(P p)
