Difference between revisions of "RapB"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RapB RapB]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=RapB RapB]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/phosphorelay.html Phosphorelay]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=rapB rapB]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 4.873   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 4.873   

Revision as of 11:51, 7 January 2014

Gene name rapB
Synonyms spo0P, ywmE
Essential no
Product response regulator aspartate phosphatase
Function control of sporulation initiation
Gene expression levels in SubtiExpress: rapB
Interactions involving this protein in SubtInteract: RapB
Function and regulation of this protein in SubtiPathways:
rapB
MW, pI 44 kDa, 4.873
Gene length, protein length 1131 bp, 377 aa
Immediate neighbours ywmF, moaA
Sequences Protein DNA DNA_with_flanks
Genetic context
RapB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
RapB expression.png




























Categories containing this gene/protein

protein modification, transcription factors and their control, phosphorelay

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU36690

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: RAP family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Sophie J Stephenson, Marta Perego
Interaction surface of the Spo0A response regulator with the Spo0E phosphatase.
Mol Microbiol: 2002, 44(6);1455-67
[PubMed:12067336] [WorldCat.org] [DOI] (P p)

Hanne Jarmer, Thomas S Larsen, Anders Krogh, Hans Henrik Saxild, Søren Brunak, Steen Knudsen
Sigma A recognition sites in the Bacillus subtilis genome.
Microbiology (Reading): 2001, 147(Pt 9);2417-2424
[PubMed:11535782] [WorldCat.org] [DOI] (P p)

Y L Tzeng, V A Feher, J Cavanagh, M Perego, J A Hoch
Characterization of interactions between a two-component response regulator, Spo0F, and its phosphatase, RapB.
Biochemistry: 1998, 37(47);16538-45
[PubMed:9843420] [WorldCat.org] [DOI] (P p)

M Perego, P Glaser, J A Hoch
Aspartyl-phosphate phosphatases deactivate the response regulator components of the sporulation signal transduction system in Bacillus subtilis.
Mol Microbiol: 1996, 19(6);1151-7
[PubMed:8730857] [WorldCat.org] [DOI] (P p)

M Perego, J A Hoch
Cell-cell communication regulates the effects of protein aspartate phosphatases on the phosphorelay controlling development in Bacillus subtilis.
Proc Natl Acad Sci U S A: 1996, 93(4);1549-53
[PubMed:8643670] [WorldCat.org] [DOI] (P p)