LevF

• Description: fructose-specific phosphotransferase system, EIIC component of the PTS
  
  

Gene name	levF
Synonyms
Essential	no
Product	fructose-specific phosphotransferase system EIIC component
Function	fructose uptake and phosphorylation
Gene expression levels in SubtiExpress: levF
Interactions involving this protein in SubtInteract: LevF
Metabolic function and regulation of this protein in SubtiPathways: levF
MW, pI	27 kDa, 4.395
Gene length, protein length	807 bp, 269 aa
Immediate neighbours	levG, levE
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

phosphotransferase systems, utilization of specific carbon sources, membrane proteins

This gene is a member of the following regulons

CcpA regulon, LevR regulon, SigL regulon

The gene

Basic information

• Locus tag: BSU27050

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: PTS permease, mannose permease (Man) family PubMed

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions: LevF-LevG

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P26381

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: levD-levE-levF-levG-sacC PubMed

• Expression browser: levF PubMed

• Sigma factor: SigL PubMed

• Regulation:
  • subject to carbon catabolite repression (CcpA, LevR) PubMed
  • induced in the presence of fructose (LevR) PubMed

• Regulatory mechanism:
  • CcpA: transcription repression PubMed
  • LevR: transcription activation PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: