Difference between revisions of "FeuC"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=FeuC FeuC]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=FeuC FeuC]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/stress_response.html Stress], [http://cellpublisher.gobics.de/view/GqbblRJkBH Metal ion homeostasis]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=feuC feuC]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 10.435   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 42 kDa, 10.435   

Revision as of 10:02, 7 January 2014

  • Description: ABC transporter for the siderophores Fe-enterobactin and Fe-bacillibactin (integral membrane protein)

Gene name feuC
Synonyms
Essential no
Product ABC transporter for the siderophores Fe-enterobactin and
Fe-bacillibactin (integral membrane protein)
Function acquisition of iron
Gene expression levels in SubtiExpress: feuC
Interactions involving this protein in SubtInteract: FeuC
Metabolic function and regulation of this protein in SubtiPathways:
feuC
MW, pI 42 kDa, 10.435
Gene length, protein length 1182 bp, 394 aa
Immediate neighbours ybbA, feuB
Sequences Protein DNA DNA_with_flanks
Genetic context
FeuC context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FeuC expression.png




























Categories containing this gene/protein

ABC transporters, acquisition of iron, iron metabolism, membrane proteins

This gene is a member of the following regulons

Btr regulon, CitB regulon, Fur regulon

The gene

Basic information

  • Locus tag: BSU01610

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: FecCD subfamily (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
    • repressed in the presence of iron (Fur, CitB) PubMed
    • induced in the presence of iron chelators bacillibactin or enterobactin (Btr) PubMed
  • Regulatory mechanism:
    • Fur: transcription repression PubMed
    • CitB: binding to the iron responsive element in the absence of iron
    • Btr: transcription activation in the presence of the co-activators bacillibactin or enterobactin PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References