Difference between revisions of "FliT"

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===Phenotypes of a mutant ===
 
===Phenotypes of a mutant ===
 +
* the mutation suppresses the mucoid phenotype of ''[[motA]]'' or ''[[motB]]'' mutants {{PubMed|24296669}}
  
 
=== Database entries ===
 
=== Database entries ===
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=== Additional information===
 
=== Additional information===
 
 
  
  
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
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* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fliT_3632150_3632491_-1 fliT] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=fliT_3632150_3632491_-1 fliT] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigD]] {{PubMed|8195064}}  
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* '''[[Sigma factor]]:''' [[SigD]] {{PubMed|8195064}}  
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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=References=
 
=References=
  
<pubmed>8195064, 20534509,</pubmed>
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<pubmed>8195064, 20534509,24296669</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 19:55, 4 December 2013

  • Description: chaperone for the export of FliD

Gene name fliT
Synonyms
Essential no
Product chaperone for FliD export
Function movement and chemotaxis
Gene expression levels in SubtiExpress: fliT
Interactions involving this protein in SubtInteract: FliT
MW, pI 13 kDa, 5.621
Gene length, protein length 339 bp, 113 aa
Immediate neighbours smiA, fliS
Sequences Protein DNA DNA_with_flanks
Genetic context
FliT context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FliT expression.png















Categories containing this gene/protein

motility and chemotaxis

This gene is a member of the following regulons

SigD regulon

The gene

Basic information

  • Locus tag: BSU35320

Phenotypes of a mutant

  • the mutation suppresses the mucoid phenotype of motA or motB mutants PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: bacillales fliT family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jia Mun Chan, Sarah B Guttenplan, Daniel B Kearns
Defects in the flagellar motor increase synthesis of poly-γ-glutamate in Bacillus subtilis.
J Bacteriol: 2014, 196(4);740-53
[PubMed:24296669] [WorldCat.org] [DOI] (I p)

Gert Bange, Nico Kümmerer, Christoph Engel, Gunes Bozkurt, Klemens Wild, Irmgard Sinning
FlhA provides the adaptor for coordinated delivery of late flagella building blocks to the type III secretion system.
Proc Natl Acad Sci U S A: 2010, 107(25);11295-300
[PubMed:20534509] [WorldCat.org] [DOI] (I p)

L Chen, J D Helmann
The Bacillus subtilis sigma D-dependent operon encoding the flagellar proteins FliD, FliS, and FliT.
J Bacteriol: 1994, 176(11);3093-101
[PubMed:8195064] [WorldCat.org] [DOI] (P p)