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| − | * '''Description:''' [[penicillin-binding protein]] 5*, D-alanyl-D-alanine carboxypeptidase <br/><br/>
| + | #REDIRECT [[PdxS]] |
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| − | {| align="right" border="1" cellpadding="2"
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| − | |style="background:#ABCDEF;" align="center"|'''Gene name'''
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| − | |''dacA''
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| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || '' ''
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| − | |style="background:#ABCDEF;" align="center"| '''Essential''' || no
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || [[penicillin-binding protein]] 5*, <br/>D-alanyl-D-alanine carboxypeptidase
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| − | |style="background:#ABCDEF;" align="center"|'''Function''' || carboxypeptidase
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00100 dacA]
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| − | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 48 kDa, 5.668
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| − | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1329 bp, 443 aa
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| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[guaB]]'', ''[[pdxS]]''
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| − | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU00100 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU00100 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU00100 DNA_with_flanks]
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| − | |colspan="2" | '''Genetic context''' <br/> [[Image:dacA_context.gif]]
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| − | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div>
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| − | |colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dacA_17534_18865_1 Expression at a glance]'''   {{PubMed|22383849}}<br/>[[Image:dacA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU00100]]
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| − | |}
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| − | __TOC__
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| − | <br/><br/><br/><br/>
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| − | <br/><br/><br/><br/>
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| − | <br/><br/><br/><br/>
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| − | <br/><br/>
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| − | = [[Categories]] containing this gene/protein =
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| − | {{SubtiWiki category|[[cell wall synthesis]]}},
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| − | {{SubtiWiki category|[[membrane proteins]]}}
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| − | = This gene is a member of the following [[regulons]] =
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| − | =The gene=
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| − | === Basic information ===
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| − | * '''Locus tag:''' BSU00100
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| − | ===Phenotypes of a mutant ===
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| − | === Database entries ===
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| − | * '''DBTBS entry:''' no entry
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| − | * '''SubtiList entry:''' [http://genolist.pasteur.fr/SubtiList/genome.cgi?gene_detail+BG10074]
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| − | === Additional information===
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| − | =The protein=
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| − | === Basic information/ Evolution ===
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| − | * '''Catalyzed reaction/ biological activity:''' Preferential cleavage: (Ac)(2)-L-Lys-D-Ala-|-D-Ala (according to Swiss-Prot)
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| − | * '''Protein family:''' peptidase S11 family (according to Swiss-Prot)
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| − | * '''Paralogous protein(s):'''
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| − | === Extended information on the protein ===
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| − | * '''Kinetic information:'''
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| − | * '''Domains:'''
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| − | * '''Modification:'''
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| − | * '''Cofactor(s):'''
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| − | * '''Effectors of protein activity:'''
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| − | * '''[[SubtInteract|Interactions]]:'''
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| − | * '''[[Localization]]:'''
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| − | ** secreted (according to Swiss-Prot), membrane associated [http://www.ncbi.nlm.nih.gov/pubmed/18763711 PubMed]
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| − | === Database entries ===
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| − | * '''Structure:'''
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| − | * '''UniProt:''' [http://www.uniprot.org/uniprot/P08750 P08750]
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| − | * '''KEGG entry:''' [http://www.genome.jp/dbget-bin/www_bget?bsu:BSU00100]
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| − | * '''E.C. number:'''
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| − | === Additional information===
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| − | =Expression and regulation=
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| − | * '''Operon:'''
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| − | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=dacA_17534_18865_1 dacA] {{PubMed|22383849}}
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| − | * '''[[Sigma factor]]:'''
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| − | * '''Regulation:'''
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| − | * '''Regulatory mechanism:'''
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| − | * '''Additional information:'''
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| − | =Biological materials =
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| − | * '''Mutant:'''
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| − | ** 1A742 ( ''dacA''::''cat''), {{PubMed|3087956}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A742&Search=1A742 BGSC]
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| − | ** 1A743 ( ''dacA''::''cat''), {{PubMed|3087956}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1A743&Search=1A743 BGSC]
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| − | * '''Expression vector:'''
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| − | * '''lacZ fusion:'''
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| − | * '''GFP fusion:'''
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| − | * '''two-hybrid system:'''
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| − | * '''Antibody:'''
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| − | =Labs working on this gene/protein=
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| − | =Your additional remarks=
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| − | =References=
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| − | <pubmed>,9864321,18763711, 23531131 </pubmed>
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| − | [[Category:Protein-coding genes]] | |
