Difference between revisions of "FtsH"

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=References=
 
=References=
 
==Reviews==
 
==Reviews==
'''Additional reviews:''' {{PubMed|23479438}}
+
<pubmed>23479438 </pubmed>
 
==Original publications==
 
==Original publications==
'''Additional publications:''' {{PubMed|22882210,22142536}}
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<pubmed>10913836,12533473,9076729,10851010,9084181,15386101,10077851,19332814,12884008,7608085,9352926,, 19332814, 18763711 12176385 18179421 24001521 22882210,22142536</pubmed>
<pubmed>10913836,12533473,9076729,10851010,9084181,15386101,10077851,19332814,12884008,7608085,9352926,, 19332814, 18763711 12176385 18179421 </pubmed>
 
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 16:10, 5 September 2013

  • Description: ATP-dependent metalloprotease

Gene name ftsH
Synonyms
Essential no
Product ATP-dependent metalloprotease
Function cell division, sporulation initiation
Gene expression levels in SubtiExpress: ftsH
Interactions involving this protein in SubtInteract: FtsH
Metabolic function and regulation of this protein in SubtiPathways:
Phosphorelay, Stress
MW, pI 70 kDa, 5.841
Gene length, protein length 1911 bp, 637 aa
Immediate neighbours hprT, coaX
Sequences Protein DNA DNA_with_flanks
Genetic context
FtsH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
FtsH expression.png















Categories containing this gene/protein

cell division, proteolysis, cell envelope stress proteins (controlled by SigM, V, W, X, Y), heat shock proteins, biofilm formation, membrane proteins

This gene is a member of the following regulons

SigM regulon

The gene

Basic information

  • Locus tag: BSU00690

Phenotypes of a mutant

  • defective in biofilm formation PubMed
  • strongly reduced sporulation frequency PubMed

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: degrades Spo0E and Spo0M, resulting in reduced sporulation frequency in a ftsH mutant PubMed
  • Protein family:
  • Paralogous protein(s): YjoB

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1LV7 (from E. coli, 64% identity) PubMed
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by heat shock (class III)
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Original publications