Difference between revisions of "MreBH"

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** [[MreBH]]-[[Mbl]] {{PubMed|21636744}}
 
** [[MreBH]]-[[Mbl]] {{PubMed|21636744}}
 
** [[MreB]]-[[MreBH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17064365 PubMed]
 
** [[MreB]]-[[MreBH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17064365 PubMed]
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** [[RodZ]]-[[MreBH]] {{PubMed|23879732}}
  
 
* '''[[Localization]]:'''  
 
* '''[[Localization]]:'''  
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mreBH_1516574_1517581_-1 mreBH] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mreBH_1516574_1517581_-1 mreBH] {{PubMed|22383849}}
  
* '''Sigma factor:''' [[SigI]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed]
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* '''[[Sigma factor]]:''' [[SigI]]  [http://www.ncbi.nlm.nih.gov/sites/entrez/18156261 PubMed]
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
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<pubmed> 17064365,  20566861 21636744,21636745 22362028 </pubmed>
 
<pubmed> 17064365,  20566861 21636744,21636745 22362028 </pubmed>
 
==Other original publications==
 
==Other original publications==
<pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484</pubmed>
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<pubmed>16950129,19643765 ,16950129 18156261, 19659933 21091501 22069484 23879732</pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 08:20, 30 July 2013

  • Description: cell shape-determining protein, forms filaments, the polymers control/restrict the mobility of the cell wall elongation enzyme complex

Gene name mreBH
Synonyms
Essential no
Product cell shape-determining protein
Function cell shape determation
Gene expression levels in SubtiExpress: mreBH
Interactions involving this protein in SubtInteract: MreBH
MW, pI 35 kDa, 5.239
Gene length, protein length 1005 bp, 335 aa
Immediate neighbours ykpC, abh
Sequences Protein DNA DNA_with_flanks
Genetic context
MreBH context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MreBH expression.png















Categories containing this gene/protein

cell shape, heat shock proteins, membrane proteins

This gene is a member of the following regulons

SigI regulon

The gene

Basic information

  • Locus tag: BSU14470

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • forms ring-shaped filaments in a heterologous system PubMed
  • Protein family: ftsA/mreB family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • during logarithmic growth, MreBH forms discrete patches thst move processively along peripheral tracks perpendicular to the cell axis PubMed
    • forms transverse bands as cells enter the stationary phase PubMed
    • close to the inner surface of the cytoplasmic membrane PubMed
    • reports on helical structures formed by MreBH PubMed seem to be misinterpretation of data PubMed
    • normal localization depends on the presence of glucolipids, MreB forms irregular clusters in an ugtP mutant PubMed

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Peter Graumann, Freiburg University, Germany homepage

Your additional remarks

References

Localization

Other original publications