Difference between revisions of "Mbl"
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** [[MreB]]-[[Mbl]] {{PubMed|21636744}} | ** [[MreB]]-[[Mbl]] {{PubMed|21636744}} | ||
** [[Mbl]]-[[MreBH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17064365 PubMed] | ** [[Mbl]]-[[MreBH]] [http://www.ncbi.nlm.nih.gov/sites/entrez/17064365 PubMed] | ||
+ | ** [[RodZ]]-[[Mbl]] {{PubMed|23879732}} | ||
* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mbl_3747254_3748255_-1 mbl] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mbl_3747254_3748255_-1 mbl] {{PubMed|22383849}} | ||
− | * '''Sigma factor:''' [[SigE]] {{PubMed|9023218}} | + | * '''[[Sigma factor]]:''' [[SigE]] {{PubMed|9023218}} |
* '''Regulation:''' | * '''Regulation:''' | ||
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<pubmed> 17064365, 20566861 21636744,21636745 22069484</pubmed> | <pubmed> 17064365, 20566861 21636744,21636745 22069484</pubmed> | ||
==Other original publications== | ==Other original publications== | ||
− | <pubmed>19643765,16832063,11290328,12809607,16101995,12530960,7836311,,16950129 9023218, 19659933 19114499, 21091501 20525796 22048160 22343529</pubmed> | + | <pubmed>19643765,16832063,11290328,12809607,16101995,12530960,7836311,,16950129 9023218, 19659933 19114499, 21091501 20525796 22048160 22343529 23879732</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 08:20, 30 July 2013
- Description: cell shape-determining protein, forms filaments, the polymers control/restrict the mobility of the cell wall elongation enzyme complex
Gene name | mbl |
Synonyms | |
Essential | no |
Product | MreB-like protein |
Function | cell shape determination |
Gene expression levels in SubtiExpress: mbl | |
Interactions involving this protein in SubtInteract: Mbl | |
MW, pI | 35 kDa, 5.669 |
Gene length, protein length | 999 bp, 333 aa |
Immediate neighbours | flhO, spoIIID |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
cell shape, sporulation proteins, membrane proteins
This gene is a member of the following regulons
SigE regulon, stringent response
The gene
Basic information
- Locus tag: BSU36410
Phenotypes of a mutant
non-viable in the presence of low Mg(2+), readily accumulate rsgI suppressor mutants PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- forms helical filaments in a heterologous system PubMed
- Protein family: ftsA/mreB family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
- during logarithmic growth, Mbl forms discrete patches that move processively along peripheral tracks perpendicular to the cell axis PubMed
- forms transverse bands as cells enter the stationary phase PubMed
- close to the inner surface of the cytoplasmic membrane PubMed
- reports on helical structures formed by Mbl PubMed seem to be misinterpretation of data PubMed
Database entries
- Structure:
- UniProt: P39751
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- An antisense RNA is predicted for mbl PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system: B. pertussis adenylate cyclase-based bacterial two hybrid system (BACTH), available in Görke lab
- Antibody: available in the Jeff Errington and Peter Graumann labs
Labs working on this gene/protein
Peter Graumann, Freiburg University, Germany homepage
Your additional remarks
References
Localization
Other original publications