Difference between revisions of "IspF"
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=== Database entries === | === Database entries === | ||
− | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1T0A 1T0A] (from ''Shewanella oneidensis'', 62% identity) {{PubMed|15502301}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/Q06756 Q06756] | * '''UniProt:''' [http://www.uniprot.org/uniprot/Q06756 Q06756] | ||
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=References= | =References= | ||
− | <pubmed>15805528, 10482513 12270818 17458547 23840410 </pubmed> | + | <pubmed>15805528, 10482513 12270818 17458547 23840410 15502301 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 15:55, 12 July 2013
- Description: 2-C-methyl-D-erythrol-2,4-cyclodiphosphate synthase, 5th step in the MEP pathway of isoprenoid biosynthesis
Gene name | ispF |
Synonyms | yacN |
Essential | yes PubMed |
Product | 2-C-methyl-D-erythrol-2,4-cyclodiphosphate synthase |
Function | MEP pathway of isoprenoid biosynthesis |
Gene expression levels in SubtiExpress: ispF | |
MW, pI | 16 kDa, 5.398 |
Gene length, protein length | 474 bp, 158 aa |
Immediate neighbours | ispD, gltX |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
biosynthesis of lipids, general stress proteins (controlled by SigB), essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU00910
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: 2-phospho-4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol = 2-C-methyl-D-erythritol 2,4-cyclodiphosphate + CMP (according to Swiss-Prot)
- Protein family: ispF family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- UniProt: Q06756
- KEGG entry: [3]
- E.C. number: 4.6.1.12
Additional information
Expression and regulation
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References