YnzC

• Description: unknown
  
  

Gene name	ynzC
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ynzC
MW, pI	8 kDa, 10.285
Gene length, protein length	231 bp, 77 aa
Immediate neighbours	yneB, tkt
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

proteins of unknown function

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

• Locus tag: BSU17880

Phenotypes of a mutant

• increased sensitivity to DNA-damaging agents PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: UPF0291 family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (according to Swiss-Prot)

Database entries

• Structure: 2HEP (NMR), 3BHP

• UniProt: O31818

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yneA-yneB-ynzC PubMed

• Expression browser: ynzC PubMed

• Sigma factor:

• Regulation:
  • induced by DNA damage (LexA) PubMed

• Regulatory mechanism:
  • LexA: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Meike Buchholz, Hannes Nahrstedt, Mike H Pillukat, Veronika Deppe, Friedhelm Meinhardt
yneA mRNA instability is involved in temporary inhibition of cell division during the SOS response of Bacillus megaterium.
Microbiology (Reading): 2013, 159(Pt 8);1564-1574
[PubMed:23728628] [WorldCat.org] [DOI] (I p)

Nora Au, Elke Kuester-Schoeck, Veena Mandava, Laura E Bothwell, Susan P Canny, Karen Chachu, Sierra A Colavito, Shakierah N Fuller, Eli S Groban, Laura A Hensley, Theresa C O'Brien, Amish Shah, Jessica T Tierney, Louise L Tomm, Thomas M O'Gara, Alexi I Goranov, Alan D Grossman, Charles M Lovett
Genetic composition of the Bacillus subtilis SOS system.
J Bacteriol: 2005, 187(22);7655-66
[PubMed:16267290] [WorldCat.org] [DOI] (P p)

Yoshikazu Kawai, Shigeki Moriya, Naotake Ogasawara
Identification of a protein, YneA, responsible for cell division suppression during the SOS response in Bacillus subtilis.
Mol Microbiol: 2003, 47(4);1113-22
[PubMed:12581363] [WorldCat.org] [DOI] (P p)