Difference between revisions of "CsoR"

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Revision as of 14:34, 16 May 2013

  • Description: transcription repressor of copZ-copA

Gene name csoR
Synonyms yvgZ
Essential no
Product transcription repressor
Function control of copper homeostasis
Gene expression levels in SubtiExpress: csoR
Metabolic function and regulation of this protein in SubtiPathways:
metal ion homeostasis
MW, pI 11 kDa, 7.299
Gene length, protein length 303 bp, 101 aa
Immediate neighbours copZ, yvaA
Sequences Protein DNA DNA_with_flanks
Genetic context
YvgZ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
CsoR expression.png















Categories containing this gene/protein

trace metal homeostasis (Cu, Zn, Ni, Mn, Mo), transcription factors and their control, resistance against toxic metals

This gene is a member of the following regulons

The CsoR regulon:

The gene

Basic information

  • Locus tag: BSU33520

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity: Cu(I) ions cause release of CsoR from its operator sites

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

John Helmann, Cornell University, USA Homepage

Mohamed Marahiel, Marburg University, Germany homepage

Your additional remarks

References

Reviews

Corinna Rademacher, Bernd Masepohl
Copper-responsive gene regulation in bacteria.
Microbiology (Reading): 2012, 158(Pt 10);2451-2464
[PubMed:22918892] [WorldCat.org] [DOI] (I p)

Original publications