Difference between revisions of "MrgA"

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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mrgA_3383565_3384026_1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:mrgA_expression.png|500px|link=http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU32990]]
 
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Revision as of 14:31, 16 May 2013

  • Description: iron storage protein, DNA-binding stress protein, forms highly stable, multimeric protein-DNA complexes which protect against oxidative killing

Gene name mrgA
Synonyms
Essential no
Product mini-ferritin, DNA-binding stress protein
Function iron storage,


protection against oxidative stress

Gene expression levels in SubtiExpress: mrgA


protection against oxidative stress

Metabolic function and regulation of this protein in SubtiPathways:
Stress
MW, pI 17 kDa, 4.597
Gene length, protein length 459 bp, 153 aa
Immediate neighbours yusZ, htrB
Sequences Protein DNA DNA_with_flanks
Genetic context
MrgA context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MrgA expression.png




























Categories containing this gene/protein

acquisition of iron, iron metabolism, resistance against oxidative and electrophile stress

This gene is a member of the following regulons

PerR regulon

The gene

Basic information

  • Locus tag: BSU32990

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: forms highly stable, multimeric protein-DNA complexes which protect against oxidative killing
  • Protein family: dps family (according to Swiss-Prot)
  • Paralogous protein(s): Dps

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s): contains an iron-sulfur cluster
  • Effectors of protein activity:

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Emilia Chiancone, Pierpaolo Ceci, Andrea Ilari, Frederica Ribacchi, Simonetta Stefanini
Iron and proteins for iron storage and detoxification.
Biometals: 2004, 17(3);197-202
[PubMed:15222465] [WorldCat.org] [DOI] (P p)

Original publications